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Endoscopy 2022; 54(05): 498-502
DOI: 10.1055/a-1646-1151
Innovations and brief communications

Peroral endoscopic myotomy for management of cricopharyngeal bars (CP-POEM): a retrospective evaluation

Sarah S. Al Ghamdi  ‡   *
1   Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States
2   Division of Gastroenterology and Hepatology, Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
,
Michael Bejjani‡   *
1   Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States
,
Oscar V. Hernández Mondragón
3   Division of Endoscopy, Specialties Hospital, National Medical Center Century XXI, Mexico City, Mexico
,
Nasim Parsa 
4   University of Missouri Health System, Columbia, Missouri, United States
,
Muhammad N. Yousaf 
5   Medstar Union Memorial Hospital, Baltimore, Maryland, United States
,
Mohammad Aghaie Meybodi
1   Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States
,
Bachir Ghandour 
1   Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States
,
Chonlada Krustri
6   Department of Surgery, Mahidol University, Bangkok, Thailand
,
Chainarong Phalanusitthepha
6   Department of Surgery, Mahidol University, Bangkok, Thailand
,
Saowanee Ngamruengphong
1   Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States
,
Jose M. Nieto
7   Borland Groover Clinic Advanced Therapeutic Endoscopy Center and Baptist Medical Center, Jacksonville, Florida, United States
,
Mouen A. Khashab
1   Division of Gastroenterology and Hepatology, Johns Hopkins Hospital, Baltimore, Maryland, United States
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Abstract

Background Cricopharyngeal bars (CPBs) are a unique etiology of oropharyngeal dysphagia. Symptomatic patients are managed with endoscopic dilation or surgical myotomy. Cricopharyngeal peroral endoscopic myotomy (CP-POEM) is an emerging technique for the management of dysphagia due to CPBs. This study evaluated technical success, clinical success, adverse events, and long-term recurrence following CP-POEM.

Methods Consecutive patients who underwent POEM for management of CPBs between May 2015 and December 2020 at four tertiary care centers were included. Primary outcome was clinical success (defined as improvement of dysphagia score to ≤ 1). Secondary outcomes were technical success, rate and severity of adverse events, procedure duration, and symptom recurrence.

Results 27 patients (mean age 69 years; 10 female) underwent CP-POEM during the study period. The most common presenting symptoms at the time of index procedure were dysphagia (26; 96.3 %) and regurgitation (20; 74.1 %). Clinical and technical success were achieved in all patients. Mild/moderate adverse events occurred in two patients (7.4 %). CP-POEM significantly reduced the median dysphagia score.

Conclusions CP-POEM was a safe and effective treatment for symptomatic CPBs. Although symptom recurrence was low, long-term outcome data are needed. CP-POEM should be considered as a management option for symptomatic CPBs at centers with POEM expertise.

* Co-first authors.


Fig. 1 s, Table 1 s



Publikationsverlauf

Eingereicht: 19. März 2021

Angenommen nach Revision: 23. Juli 2021

Artikel online veröffentlicht:
28. Oktober 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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