Subscribe to RSS
Endoscopic closure of cecal fistula using purse-string suture after plombage with polyglycolic acid sheets and fibrin glue
An 86-year-old man with a postappendectomy abscess and fistula was treated with antibiotics and percutaneous drainage for 5 weeks, but the fistula did not close ([Fig. 1], [Fig. 2 a]). We report successful fistula closure using a modified endoscopic closure technique ([Video 1]).
Video 1 Combination endoscopic closure technique for postappendectomy fistula. After endoscopic plombage with polyglycolic acid sheets and fibrin glue, the mucosa around the fistula was sutured with an endoloop and clips.
Polyglycolic acid (PGA) sheets (Neoveil; Gunze, Kyoto, Japan) were cut into 5 × 5-mm pieces and delivered into the fistula through the working channel of an endoscope using biopsy forceps. Then, five pieces of PGA sheet were inserted into the fistula, and fibrin glue (Beriplast P Combi-Set; CSL Behring Pharma, Tokyo, Japan) was sprayed via a tube inserted into the fistula. Finally, the endoscope was changed to a two-channel endoscope. A detachable snare (Endoloop; Olympus, Tokyo, Japan) was anchored with clips to the mucosa around the fistula and tightened to prevent the PGA sheet pieces from falling into the cecal lumen. Radiography showed improvement of the abscess cavity at the beginning of oral feeding on postoperative day 5 ([Fig. 2 b]).
Closure using over-the-scope clips (Ovesco Endoscopy, Tübingen, Germany) has been a standard treatment option for gastrointestinal (GI) fistulas, but its success rate is not necessarily high  . PGA sheets and fibrin glue have been reported as useful for treating GI fistulas  , but most reports describe successful closure in the upper GI tract; few have reported on lower GI fistulas. It is difficult to keep PGA sheets within lower GI fistulas because of peristalsis and stool. An endoscopic purse-string suture with an endoloop and clips closes large mucosal defects or perforations  but cannot close fistulas because of the fibrosis surrounding the orifice. Our modified technique combining the above two methods, which complement each other, resulted in complete closure of this patient’s refractory lower GI fistula. This technique is a viable and effective alternative option for closing a cecal fistula.
Endoscopy E-Videos is an open access online section, reporting on interesting cases and new techniques in gastroenterological endoscopy. All papers include a high quality video and all contributions are freely accessible online. Processing charges apply (currently EUR 375), discounts and wavers acc. to HINARI are available.
This section has its own submission website at https://mc.manuscriptcentral.com/e-videos
Article published online:
15 February 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
- 1 Shoar S, Poliakin L, Khorgami Z. et al. Efficacy and safety of the over-the-scope clip (OTSC) system in the management of leak and fistula after laparoscopic sleeve gastrectomy: a systematic review. Obes Surg 2017; 27: 2410-2418
- 2 Kobara H, Mori H, Nishiyama N. et al. Over-the-scope clip system: a review of 1517 cases over 9 years. J Gastroenterol Hepatol 2019; 34: 22-30
- 3 Takimoto K, Hagiwara A. Filling and shielding for postoperative gastric perforations of endoscopic submucosal dissection using polyglycolic acid sheets and fibrin glue. Endosc Int Open 2016; 4: E661-E664
- 4 Nakano Y, Takao T, Morita Y. et al. Endoscopic plombage with polyglycolic acid sheets and fibrin glue for gastrointestinal fistulas. Surg Endosc 2019; 33: 1795-1801
- 5 Zhang Y, Wang X, Xiong G. et al. Complete defect closure of gastric submucosal tumors with purse-string sutures. Surg Endosc 2014; 28: 1844-1851