Medikamentös-induzierte Polyneuropathien durch Chemotherapeutika und Antiinfektiva

Polyneuropathien können durch zahlreiche Wirkstoffe hervorgerufen oder aggraviert werden. Insbesondere die Chemotherapeutika-induzierte Polyneuropathie (CIPN) ist im Alltag von hoher Relevanz. Jedoch kann auch der Einsatz von Antiinfektiva zu neuropathischen Beschwerden führen. Im Folgenden soll ein Überblick über die wichtigsten mit Polyneuropathien assoziierten Wirkstoffe der Substanzklassen sowie die klinischen Charakteristika gegeben werden.

Abstract

Polyneuropathies are associated with numerous medications. Chemotherapy-induced polyneuropathy (CIPN) is highly relevant in clinical routine. However, treatment with anti-infectives can also lead to neuropathic symptoms. Here, we provide an overview of the most relevant drugs of these substance classes associated with polyneuropathies as well as the clinical characteristics.

Schlüsselwörter

Chemotherapie - Antibiotikum - Polyneuropathie - Nebenwirkung - Antiinfektiva

Key words

chemotherapy - antibiotic - polyneuropathy - side effect - anti-infectives

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