Abstract
Iatrogenic keratectasia is induced thinning and protrusion of the cornea after laser
refractive surgery. Known risk factors include an excessively thin postoperative residual
stromal bed, a thicker flap, or preoperatively undetected evidence of preexisting
subclinical keratoconus. The rate of post-refractive ectasia in eyes without identifiable
preoperative risk factors is 20 per 100 000 eyes for photorefractive keratectomy,
90 per 100 000 eyes for laser in situ keratomileusis, and 11 per 100 000 eyes for small incision lenticule extraction.
Traditional screening tools for preoperative risk include the ectasia risk score system
and percentage of tissue alteration. More recent methods include corneal elastography
and epithelial mapping, in addition to Artificial Intelligence methods for data analysis.
Therapy includes contact lenses, cross-linking, implantation of intracorneal ring
segments, penetrating or lamellar keratoplasty, and, in early studies, implantation
of
corneal lenticules.
Key words
cornea - refractive surgery - ectasia