Translational Research Techniques for the Facial Plastic Surgeon: An Overview

William Mason; Albert M. Levin; Katherine Buhl; Takahiro Ouchi; Bianca Parker; Jessica Tan; Nureddin Ashammakhi; Lamont R. Jones

doi:10.1055/a-2113-5023

Facial Plastic Surgery, Inhaltsverzeichnis

Facial Plast Surg 2023; 39(05): 466-473
DOI: 10.1055/a-2113-5023

Original Article

Translational Research Techniques for the Facial Plastic Surgeon: An Overview

Authors

William Mason

¹Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
Albert M. Levin

²Department of Public Health Science, Henry Ford Health, Detroit, Michigan

³Center for Bioinformatics, Henry Ford Health, Detroit, Michigan
Katherine Buhl

¹Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
Takahiro Ouchi

¹Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
Bianca Parker

¹Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
Jessica Tan

¹Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan
Nureddin Ashammakhi

⁴Institute for Quantitative Health Science and Engineering, Michigan State University, Michigan

⁵Department of Biomedical Engineering, College of Engineering, Michigan State University, Michigan

⁶College of Human Medicine, Michigan State University, Michigan
Lamont R. Jones

¹Department of Otolaryngology, Henry Ford Hospital, Detroit, Michigan

Abstract

The field of facial plastic and reconstructive surgery (FPRS) is an incredibly diverse, multispecialty field that seeks innovative and novel solutions for the management of physical defects on the head and neck. To aid in the advancement of medical and surgical treatments for these defects, there has been a recent emphasis on the importance of translational research. With recent technological advancements, there are now a myriad of research techniques that are widely accessible for physician and scientist use in translational research. Such techniques include integrated multiomics, advanced cell culture and microfluidic tissue models, established animal models, and emerging computer models generated using bioinformatics. This study discusses these various research techniques and how they have and can be used for research in the context of various important diseases within the field of FPRS.

Keywords

translational research - multiomics - facial plastic and reconstructive surgery - keloid disease

Volltext

Referenzen

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