MASLD – Prävention und ernährungsmedizinische Behandlungsmöglichkeiten

Zusammenfassung

Diese Übersicht nutzt die neue Nomenklatur der Fettlebererkrankungen, die im Juni 2023 von der amerikanischen Lebergesellschaft AASLD und der europäischen Lebergesellschaft EASL in einem umfangreichen Konsensusverfahren etabliert wurde. Die Deutsche Gesellschaft für Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten (DGVS) unterstützt die neue Namensgebung mit Nachdruck.

Körperliche Inaktivität, zunehmendes Körpergewicht und höheres Lebensalter haben in den letzten Jahrzehnten zu einem Anstieg der Prävalenz der metabolischen Dysfunktion assoziierten Fettlebererkrankung (MASLD) geführt. In vielen Industrieländern ist die MASLD inzwischen die häufigste chronische Lebererkrankung. MASLD ist eine Form der steatotischen Lebererkrankung, die eng mit Stoffwechselkrankheiten wie Typ-2-Diabetes, Dyslipidämie und Adipositas verbunden ist. Sie wird daher auch als metabolisch assoziierte Fettleber bezeichnet [1].

Abstract

This review uses the new nomenclature of fatty liver diseases established in June 2023 by the American liver society AASLD and the European liver society EASL in a comprehensive consensus process. The German Society for Gastroenterology, Digestive and Metabolic Diseases (DGVS) strongly supports the new naming.

Physical inactivity, increasing body weight and older age have caused an increase in the prevalence of metabolic dysfunction associated fatty liver disease (MASLD) in recent decades. In many industrialized countries MASLD is now the most common chronic liver disease. MASLD represents a form of steatotic liver disease closely associated with metabolic diseases such as type 2 diabetes, dyslipidemia, and obesity. It is therefore also referred to as metabolically associated fatty liver.

Schlüsselwörter

Fettleber - MASLD - mediterrane Ernährung - Insulinresistenz

Key words

fatty liver - MASLD - mediterranean diet - insulin resistance

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