Dear Editor,
The authors thank the writers [1] of the
letter for reviewing and assessing our article [2], “Prolactin is a Key Factor for Nonalcoholic Fatty Liver Disease in
Obese Children”. Overall, we agree that possible selection bias must be considered.
However, in clinical studies, we found that hyperprolactinemia is mainly caused by
pathological and idiopathic hyperprolactinemia. The former includes hypothalamic
pituitary lesions (pituitary prolactinoma and empty sella syndrome, etc.), systemic
diseases (hypothyroidism, etc.), tumor secretion (ovarian teratoma, etc.), trauma
(chest wall trauma, etc.), surgery (artificial abortion, etc.), and drug side
effects (antipsychotics, antidepressants, etc.).
