Solvent-Free Approaches for the Synthesis of Lophine Derivatives

Shiv R. Desai; Sachin G. Modha

doi:10.1055/a-2421-7430

Sustainability & Circularity NOW, Table of Contents

CC BY 4.0 · Sustainability & Circularity NOW 2024; 01: a24217430
DOI: 10.1055/a-2421-7430

Short Review

Solvent-Free Approaches for the Synthesis of Lophine Derivatives

Authors

Shiv R. Desai

¹Laboratory of Organic Chemistry, Tarsadia Institute of Chemical Science, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli-Mahuva Road, Tarsadi, 394350 Surat, Gujarat, India
Sachin G. Modha

¹Laboratory of Organic Chemistry, Tarsadia Institute of Chemical Science, Uka Tarsadia University, Maliba Campus, Gopal Vidyanagar, Bardoli-Mahuva Road, Tarsadi, 394350 Surat, Gujarat, India

Abstract

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Abstract

Solvent-free synthesis comes with many advantages such as cost reduction, waste reduction, ease of operation, sustainability, environmentally benign operations, etc. These benefits have prompted many chemists to develop new protocols for solvent-free synthesis of various interesting chemical compounds. One such class of compounds is 2,4,5-triarylimidazoles, commonly known as lophines due to their applications in materials science, chemo- and bio-sensors, and pharmacology. This article focuses on solvent-free synthesis of lophine derivatives via different protocols, including the use of inorganic-, organic-, and biocatalysts; solid-supported catalysts; microwave-mediated heating; and grinding.

Keywords

Lophine - Triaryl imidazoles - Imidazoles - Solvent-free - Neat - Sustainable chemistry - Green chemistry - Multicomponent reactions

Bibliographical Record
Shiv R. Desai, Sachin G. Modha. Solvent-Free Approaches for the Synthesis of Lophine Derivatives. Sustainability & Circularity NOW 2024; 01: a24217430.
DOI: 10.1055/a-2421-7430

Full Text

References

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