Author commentary on Eisuke Nakao et al.

Eisuke Nakao et al. Randomized controlled trial of an artificial intelligence diagnostic system for the detection of esophageal squamous cell carcinoma in clinical practice

The potentially enhanced detection rate of esophageal squamous cell carcinoma (ESCC) with AI was assessed in this randomized controlled trial. A total of 320 high risk patients with ESCC undergoing screening or surveillance esophagogastroduodenoscopy were randomly allocated to AI or control groups. Nonexpert detection rates for ESCC were 47% (with AI) and 45% (control group), with no significant difference. In this study AI appeared not to be of added value for ESCC detection by nonexperts in clinical practice.

Publication History

Article published online:
26 February 2025