Synthesis, Table of Contents Synthesis 2025; 57(13): 2105-2114DOI: 10.1055/a-2518-0987 paper Bürgenstock Special Section 2023 – Future Stars in Organic Chemistry EDA Complexation of Two Donor Molecules Initiating Radical Cation Cyclizations Authors Julian C. G. Kürschner‡ Martin Utikal‡ Lena Lezius Rubaishan Jeyaseelan Line Næsborg ∗ Recommend Article Abstract Buy Article(opens in new window) All articles of this category(opens in new window) Abstract In this study, a catalyst-free EDA complexation of two donor molecules using an acidic solvent is presented. The electron-rich aromatic compound (E)-anethole is slowly protonated by the solvent hexafluoroisopropanol (HFIP), leading to the rapid formation of a photoactive EDA complex between a protonated (E)-anethole and another (E)-anethole molecule. This resulting EDA complex initiates radical chain cyclization reactions under green light irradiation. 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