Abstract
Ocular mucosal pemphigoid is a rare, chronically progressive autoimmune disease of
the ocular surface. It belongs to a group of diseases whose common clinical correlate
is the disruption of cohesion at the basement membrane. Recurrent inflammation with
progressive fibrosis of the conjunctiva and damage to limbal stem cells are characteristic.
If the course remains uncontrolled, severe morphological and functional damage can
occur, up to blindness. Therefore, the critical perception of initially subtle findings
and early diagnostic are of great importance. The aim of immune modulative therapy
is to control the underlying inflammation and prevent the progression of fibrosis,
in order to avoid serious complications.
Keywords
autoimmune diagnostics - ocular pemphigoid - mucosal pemphigoid - symblepharon - scarring
conjunctivitis
