Treatment of Patients with Early Breast Cancer

Michael Untch; Maggie Banys-Paluchowski; Sara Y. Brucker; Carsten Denkert; Peter A. Fasching; Renate Haidinger; Nadia Harbeck; Wolfgang Janni; David Krug; Sibylle Loibl; Diana Lüftner; Laura Michel; Eva Schumacher-Wulf; Christine Solbach; Rachel Würstlein; Jens Huober; Nina Ditsch

doi:10.1055/a-2612-3790

Geburtshilfe und Frauenheilkunde, Inhaltsverzeichnis

CC BY-NC-ND 4.0 · Geburtshilfe Frauenheilkd 2025; 85(07): 677-693
DOI: 10.1055/a-2612-3790

GebFra Science

Review/Übersicht

Treatment of Patients with Early Breast Cancer

19th St. Gallen International Breast Cancer Consensus Discussed against the Background of German Treatment Recommendations Artikel in mehreren Sprachen: English | deutsch

Authors

Michael Untch^*

¹Medical School Berlin, Klinik für Gynäkologie und Geburtshilfe, Interdisziplinäres Brustzentrum, HELIOS Klinikum Berlin Buch, Berlin, Germany
Maggie Banys-Paluchowski^*

²Klinik für Frauenheilkunde und Geburtshilfe, Brustzentrum, Campus Lübeck, Universitätsklinikum Schleswig-Holstein, Lübeck, Germany
Sara Y. Brucker^**

³Universitäts-Frauenklinik Tübingen, Tübingen, Germany
Carsten Denkert^**

⁴Institut für Pathologie, Philipps-Universität Marburg und Universitätsklinikum Marburg (UKGM), Marburg, Germany
Peter A. Fasching^*

⁵Frauenklinik des Universitätsklinikums Erlangen, Comprehensive Cancer Center Erlangen-EMN, Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
Renate Haidinger^P

⁶Brustkrebs Deutschland e. V., Hohenbrunn bei München, Germany
Nadia Harbeck^*^**

⁷Brustzentrum, Frauenklinik, CCC München, LMU Klinikum München, München, Germany
Wolfgang Janni^*^**

⁸Universitätsfrauenklinik Ulm, Ulm, Germany
David Krug^*

⁹Klinik für Strahlentherapie und Radioonkologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany
Sibylle Loibl^**

¹⁰German Breast Group (GBG), Neu-Isenburg; Goethe Universität, Frankfurt am Main, Germany
Diana Lüftner^*

¹¹Immanuel Klinik Märkische Schweiz, Buckow & Immanuel Klinik Rüdersdorf, Medizinische Hochschule Brandenburg, Rüdersdorf bei Berlin, Germany
Laura Michel^**

¹²Gynäkologische Onkologie, Nationales Centrum für Tumorerkrankungen (NCT) Heidelberg, Heidelberg, Germany
Eva Schumacher-Wulf^P

¹³Mamma Mia! Brustkrebsmagazin, Köln, Germany
Christine Solbach^**

¹⁴Klinik für Frauenheilkunde und Geburtshilfe; Brustzentrum, Universitätsmedizin Frankfurt, Frankfurt am Main, Germany
Rachel Würstlein^*

¹⁵Brustzentrum, Frauenklinik, LMU Klinikum München, München, Germany
Jens Huober^*^**

¹⁶HOCH, Brustzentrum Kantonsspital St. Gallen, St. Gallen, Switzerland
Nina Ditsch^*

¹⁷Frauenheilkunde, Geburtshilfe und Senologie, Medizinische Fakultät, Universität Augsburg, Brustzentrum, Universitätsklinikum Augsburg, Augsburg, Germany

Abstract

This yearʼs 19th St. Gallen (SG) consensus conference on the treatment of patients with early breast cancer (SGBCC: St. Gallen Breast Cancer Conference) is based on numerous patient examples, each with different variables, to reflect the increasingly personalized treatment decision for early breast cancer. More than ever, not only breast cancer subtype, performance status, age and life expectancy are considered as individual factors, but various molecular and genetic variables are also part of the treatment decision. In this manuscript, the SGBCC voting results are discussed by a German group of breast cancer specialists in the context of the recently (2025) updated treatment recommendations of the Commission of the Gynecological Oncology Working Group (AGO Mamma). The German treatment recommendations are based on current evidence. As the international panel of the SGBCC consists of experts from different countries and disciplines, the votes represent an international cross-section of opinions. Therefore, it is useful to discuss the voting results with respect to current German treatment guidelines.

Keywords

St. Gallen Consensus 2025 - early breast cancer - genetics - surgery - radiotherapy - (neo)adjuvant systemic therapy - survivorship

Volltext

Referenzen

References/Literatur
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