Factors Influencing Clinical Trials of Herbal Medicinal Products – Using Ginger as Example

Ingrid Hook; Liselotte Krenn; Barbara Steinhoff; Evelyn Wolfram

doi:10.1055/a-2686-6315

Planta Medica, Table of Contents

Planta Med
DOI: 10.1055/a-2686-6315

Reviews

Factors Influencing Clinical Trials of Herbal Medicinal Products – Using Ginger as Example

Authors

Ingrid Hook

¹School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, University of Dublin, Dublin, Ireland

²ESCOP, Notaries House, Exeter, UK
Liselotte Krenn

²ESCOP, Notaries House, Exeter, UK

³Division of Pharmacognosy, University Vienna, Austria
Barbara Steinhoff

²ESCOP, Notaries House, Exeter, UK
Evelyn Wolfram

²ESCOP, Notaries House, Exeter, UK

⁴Natural Products and Phytopharmacy Research Group, Institute of Chemistry & Biotechnology, Zürich University of Applied Sciences, Wädenswil, Switzerland

Abstract

Ginger (Zingiber officinale) has a global use as a spice, an ingredient of beverages, food supplements (syn. dietary supplements), as well as herbal medicinal products. Since the last update of ginger in ESCOP Monographs in 2009 a significant number of papers concerning its bioactive constituents and clinical uses have been published. From this large number and selecting those references (almost 500) considered most relevant to clinical aspects and therapeutic indications, the following issues are considered to be potentially important to research on other medicinal plants: [i] quality assessment; [ii] pre-clinical (in vivo) studies; [iii] quality of clinical trials; [iv] ethnicity of clinical trial participants and [v] effects of sex-gender on activity and therapeutic indications.

Keywords

Ginger - Zingiber officinale - Zingiberaceae - factors influencing clinical trials

Full Text

References

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