Abstract
Magnetic resonance imaging (MRI) remains an integral diagnostic tool in multiple sclerosis
(MS), for both making the initial diagnosis and monitoring for disease relapse and
progression. Despite the applied use of MRI according to the revised McDonald's criteria
in 2017, there has been persistent low diagnostic specificity, especially as it pertains
to differentiating radiologically isolated syndrome from alternative diagnoses that
mimic demyelination. This report will provide an overview of recent paraclinical innovations,
with a focus on MRI biomarkers and parameters such as the central vein and paramagnetic
rim signs. Utilizing these tools in clinical practice will hopefully improve precision
in the diagnosis and monitoring of MS and reduce the risk of false-positive diagnoses.
Keywords
multiple sclerosis - magnetic resonance imaging - central vein - paramagnetic rim
