The construction of nitrogen-rich heterocycles is a cornerstone in developing high-energydensity
materials (HEDMs). Ethyl 3-ethoxy-3-iminopropanoate hydrochloride (EEIP . HCl) has
proven to be a particularly powerful precursor, offering a reliable and versatile
route to make several nitrogen rich frameworks. Its ability to streamline ring formation
has enabled the synthesis of high-performing energetic compounds with desirable densities,
stabilities, and detonation properties. This article reviews EEIP-mediated cyclization's
in energetic materials, underscoring its exceptional synthetic utility, broad structural
scope, and growing role in advancing next-generation, environmentally sustainable
explosives.
