Author commentary on Charlotte N. Frederiks et al.

Charlotte N. Frederiks et al. Endoscopic eradication therapy with multifocal cryoballoon ablation for Barrett esophagus-related neoplasia: a prospective European multicenter study

In 107 patients with dysplastic Barrett esophagus, focal cryoballoon ablation achieved complete eradication of dysplasia and intestinal metaplasia in 94% and 91% of patients, respectively, after a median of teo ablation sessions. Overall, 13% developed a stricture, with number of ablations being a risk factor. Comparison with other ablation techniques and modalities, especially for stricture reduction, is needed.

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Publication History

Article published online:
20 March 2026