DMW - Deutsche Medizinische Wochenschrift, Inhaltsverzeichnis Dtsch Med Wochenschr 2008; 133(30): 1589-1591DOI: 10.1055/s-0028-1082772 Kommentare | CommentaryHepatologie© Georg Thieme Verlag KG Stuttgart · New YorkHepatitis-B-Viruslast als Risikofaktor für eine LeberzirrhoseHepatitis B viral load as a risk factor for liver cirrhosisR. Thimme1 1Abteilung Innere Medizin II, Medizinische Universitätsklinik Freiburg Artikel empfehlen Abstract Artikel einzeln kaufen Schlüsselwörter Hepatitis B - Viruslast - Leberzirrhose Key words hepatitis B - viral load - liver cirrhosis Volltext Referenzen Literatur 1 Chen C J, Yang H I, Su J, Jen C L, You S L, Lu S N, Huang G T, Iloeje U H. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA. 2006; 295 65-73 2 Chen G, Lin W, Shen F, Iloeje U H, London W T, Evans A A. Past HBV viral load as predictor of mortality and morbidity from HCC and chronic liver disease in a prospective study. Am J Gastroenterol. 2006; 101 1797-803 3 Fattovich G, Olivari N, Pasino M, D’Onofrio M, Martone E, Donato F. Long-term outcome of chronic hepatitis B in Caucasian patients: mortality after 25 years. Gut. 2008; 57 84-90 4 Giovanna F, Bortolotti F, Francesco D. Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors. J Hepatol. 2008; 48 335-52 5 Iloeje U H, Yang H I, Su J, Jen C L, You S L, Chen C J. Predicting cirrhosis risk based on the level of circulating hepatitis B viral load. Gastroenterology. 2006; 130 678-86 6 Lai M, Hyatt B J, Nasser I, Curry M, Afdhal N H. The clinical significance of persistently normal ALT in chronic hepatitis B infection. J Hepatol. 2007; 47 760-7 7 Lin C L, Liao L Y, Liu C J, Yu M W, Chen P J, Lai M Y, Chen D S, Kao J H. Hepatitis B viral factors in HBeAg-negative carriers with persistently normal serum alanine aminotransferase levels. Hepatology. 2007; 45 1193-8 8 Lok A S, McMahon B J. Chronic hepatitis B. Hepatology. 2007; 45 507-39 9 Manno M, Camma C, Schepis F, Bassi F, Gelmini R, Giannini F, Piselli F, Grottola A, Ferretti I, Vecchi C, De Palma M, Villa E. Natural history of chronic HBV carriers in northern Italy: morbidity and mortality after 30 years. Gastroenterology. 2004; 127 756-63 10 Thimme R, Spangenberg H C, Blum H E. Chronische Hepatitis B. Dtsch Med Wochenschr. 2008; 133 135-8 11 Wedemeyer H, Cornberg M, Protzer U, Berg T, Dollinger M M. German guidelines on diagnosis and therapy of hepatitis B. Dtsch Med Wochenschr. 2007; 132 1775-82 12 Yang H I, Lu S N, Liaw Y F, You S L, Sun C A, Wang L Y, Hsiao C K, Chen P J, Chen D S, Chen C J. Hepatitis B e antigen and the risk of hepatocellular carcinoma. N Engl J Med. 2002; 347 168-74 Prof. Dr. Robert Thimme Abteilung Innere Medizin II, Medizinische Universitätsklinik Hugstetter Str. 55 79106 Freiburg eMail: robert.thimme@uniklinik-freiburg.de