Download PDF
Horm Metab Res 1979; 11(1): 23-26
DOI: 10.1055/s-0028-1092675
Originals

© Georg Thieme Verlag KG Stuttgart · New York

Enhancement of Leucine-lnduced Insulin Secretion by Somatostatin Antiserum Pretreatment

H.  Taniguchi , M.  Hasegawa , T.  Kobayashi , Y.  Watanabe , K.  Murakami , M.  Seki , A.  Tsutou , M.  Utsumi , H.  Makimura , M.  Sakoda , S.  Baba
  • Second Department of Internal Medicine, Kobe University School of Medicine, Kobe, Japan
Further Information

Publication History

Publication Date:
17 December 2008 (online)

Also available at
 PDF Download  Permissions and Reprints

Abstract

Insulin secretion induced by leucine and leucine plus glucose from rat pancreatic islets was enhanced by prior treatment with somatostatin antiserum as compared with normal rabbit serum in vitro. The results provide evidence that somatostatin plays an important role in insulin secretion in rats.

Key words

Insulin Secretion - Leucine - Somatostatin - Somatostatin Antiserum - Isolated Islet - In Vitro