© Georg Thieme Verlag KG Stuttgart · New York
Adrenocortical Responsiveness to Physiological Amounts of β1-24 ACTHII. Effect of Acute Corticotrophin Treatment in Patients Receiving Prolonged Glucocorticoid Therapy
07 January 2009 (online)
Adrenocortical responsiveness was assessed in ten asthmatic patients treated with corticosteroids for at least one year. After an acute treatment with tetracosactrin (0.25 mg every six hours for two days), both the adrenocortical responses to physiological-like amounts of β1-24ACTH and the capacity of maximal response were significantly increased. However, the adrenocortical sensitivity remained altered.
Adrenocortical Sensitivity - Plasma Cortisol - Tetracosactrin - Acute ACTH Treatment - Long-Term Glucocorticoid Treatment.