Complete normalization of the elevated fasting serum growth hormone and the abnormally
high serum growth hormone response to exercise was obtained after a period of exceedingly
strict metabolic control in five newly diagnosed male juvenile diabetics. The glomerular
filtration rate, which also was elevated in the juvenile diabetics, decreased simultaneously
to nearly normal levels. It is concluded that the abnormalities in serum growth hormone
and glomerular filtration rate are of metabolic origin and it is suggested that the
high serum growth hormone level is responsible for the high glomerular filtration
rate found in these patients.
Diabetes - Growth Hormone - Glomerular Filtration Rate
