Lactic acid stimulates the release of glycerol significantly in vitro in the resting
muscle. Although glycerol release is enhanced by lactate there are no FFA released
into the medium. In contrast high concentration of lactate in the medium stimulates
the uptake of FFA into the muscle significantly. In the presence of glucose lactate
promotes the resynthesis of glycogen. The influences of lactic acid upon the muscle
metabolism are discussed. It may be speculated that the elevated concentration of
lactate increases the supply of substrates in muscle during exercise.
Muscle Metabolism - Exercise - Self-regulating Muscle Factor - Lactate - Glycerol
Release - Free Fatty Acid Uptake
