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Planta Med 1979; 37(9): 15-19
DOI: 10.1055/s-0028-1097289
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Effect of Ginseng Saponin on Rat Adrenal Cyclic AMP

Susumu Hiai, Schinichi Sasaki, Hikokichi Oura
  • Department of Biochemistry, Research Institute for WAKAN–YAKU, Toyama University, Toy am a, Japan.
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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

Ihtraperitoneal administration of saponin preparation extracted from the roots of Panax ginseng C. A. Meyer delete increased adrenal cyclic AMP in a dose dependent manner and increased plasma 11–hydroxycorticosteroid in intact rats. In hypophysectomized rats, saponin treatment did not increase adrenal cyclic AMP whereas corticotropin treatment did. It was thereby concluded that ginseng saponin indirectly stimulated the adrenocortical function in intact . rats.

Key Word Index

Panax ginseng - Araliaceae - Saponin - Adrenal Gland - Cyclic AMP - Hypophysectomized Rats - Plasma Corticosteroids

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