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Planta Med 1973; 24(6): 133-144
DOI: 10.1055/s-0028-1099480
© Georg Thieme Verlag Stuttgart · New York

PRELIMINARY PHYTOCHEMICAL AND PHARMACOLOGICAL INVESTIGATIONS OF THE ROOTS OF DIFFERENT VARIETIES OF CICHORIUM INTYBUS

S. I. Balbaa, A. Y. Zaki, S. M. Abdel–Wahab, E. S. M. El–Denshary, M. Motazz–Bellah
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Publication Date:
14 January 2009 (online)

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Abstract

Eight varieties of Cichorium intybus were examined. Preliminary chemical screening revealed that the eight varieties are similar qualitatively in their constituents. Preliminary pharmacological study on isolated toad's heart showed that the eight varieties have a quinidine like action, but with variable potency. The site of action was determined on a representative sample where it produced effect after blocking the ganglia and after atropinisation. A colorimetric assay using Baljet's reagent was suggested for estimation of active constituents of 8 varieties where a correlation with biological assay was found.

Effect of drying and different solvent extractives on activity of the drug was also determined.

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