Zusammenfassung
Rheumatische Erkrankungen können in unterschiedlichem
Ausmaß die Reproduktion, den Verlauf einer Schwangerschaft
und die Entwicklung der Frucht beeinflussen. Die entzündlich-rheumatische
Erkrankung selbst ist häufig in ihrer Aktivität
verändert, wobei es sowohl zu klinischen Besserungen als
auch zu Schüben kommen kann. Am Beispiel der rheumatoiden
Arthritis, der ankylosierenden Spondylitis, der Arthritis psoriatica
und des systemischen Lupus erythematodes sollen die Beziehungen
zwischen Rheuma und Schwangerschaft aufgezeigt werden. Die antirheumatische
Pharmakotherapie in der Schwangerschaft und der Stillperiode muss
kritisch angepasst werden.
Summary
Rheumatic diseases can influence the reproduction, the course
of pregnancy and the development of the fetus. The inflammatory
rheumatic disease itself can be modulated in its activity in terms
of amelioration or exacerbation of the rheumatic symptoms. The associations
between rheumatic diseases and pregnancy will be illustrated with
rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis,
and systemic lupus erythematosus as examples. Antirheumatic drug
therapy during pregnancy and the breast feeding period has to be
adapted critically.
Schlüsselwörter
Rheumatische Erkrankungen - Schwangerschaft - Pharmakotherapie
Keywords
rheumatic diseases - pregnancy - pharmacotherapy
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Prof. Dr. med. Elisabeth Märker-Hermann
Klinik Innere Medizin IV (Rheumatologie,
klinische Immunologie und Nephrologie), HSK Dr. Horst Schmidt Klinik
GmbH
Ludwig-Erhard-Str. 100
65199 Wiesbaden
Phone: 0611/436445
Fax: 0611/436464
Email: Elisabeth.Maerker-Hermann@HSK-Wiesbaden.de