Horm Metab Res 2009; 41(2): 168-170
DOI: 10.1055/s-0028-1112139
Short Communication

© Georg Thieme Verlag KG Stuttgart · New York

Prevalence for the Cluster of Risk Factors of the Metabolic Vascular Syndrome in a Working Population in Germany

U. Rothe 1 , G. Müller 1 , S. Tselmin 2 , C. Odenbach 3 , K. Scheuch 3 , R. Koch 1 , S. Bergmann 4 , M. Walter 6 , A. Bergmann 5 , S. R. Bornstein 2 , P. E. H. Schwarz 2
  • 1Institute for Medical Informatics and Biometrics, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
  • 2Department of Medicine III, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
  • 3Institute for Occupational Health Care, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
  • 4Institute for Clinical Chemistry and Laboratory Medicine, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
  • 5Department of General Medicine, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
  • 6Department of Prosthetic Dentistry, Technical University Dresden, Medical Faculty Carl Gustav Carus, Dresden, Germany
Further Information

Publication History

received 29.08.2008

accepted 09.12.2008

Publication Date:
19 December 2008 (online)

Background

For the last 50 years we have observed an increasing prevalence of a cluster of diseases in the general population – obesity, type 2 diabetes, hypertension, and dyslipidemia – which are closely interrelated and strongly depend on environmental factors [1] [2]. The association of type 2 diabetes and cardiovascular diseases led to the hypothesis that both arise from common soil like abdominal obesity and insulin resistance and other common risk factors [3]. The biological mechanisms interlinking the two diseases remain unclear. Plausible pathophysiological mechanisms involve direct neuroendocrine effects and indirect effects mediated by adverse health behaviors [4] [5]. The so called Metabolic Vascular Syndrome (MVS) – specified with a Practical Guideline Metabolic Vascular Syndrome – describes a cluster of risk factors for cardiovascular diseases and type 2 diabetes like abdominal obesity, insulin resistance, atherogenic dyslipidemia, high blood pressure, and prothrombotic and proinflammatory states in adherence to the definition of the National Cholesterol Education Program – adult treatment panel III (ATPIII) – but added by the postprandial plasma glucose. Occupational stress has been linked with coronary heart disease in retrospective and prospective studies [6]. Previous studies showed that the social background determines the association between occupational stress and the MVS. Accordingly less advantaged social groups are afflicted by a high prevalence of the MVS as well as heart disease possibly attributed to greater exposure to occupational stress [7]. In some cross-sectional studies occupational stress was linked with components of the syndrome, but this association is not consistent throughout [8] [9]. The present study was aimed to assess the prevalence of the MVS and its single components within an occupational health care setting.

References

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  • 2 Hanefeld M, Ceriello A, Schwarz PE, Bornstein SR. Horm Metab Res. 2006;  38 435-436
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  • 10 Li J, Bergmann A, Reimann M, Bornstein SR, Schwarz PE. Horm Metab Res. 2008 Oct;  , 29 [Epub ahead of print]
  • 11 Schwarz PE, Bornstein SR, Hanefeld M. Diabetes Res Clin Pract. 2007;  77 148-150
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  • 13 Schwarz PE, Muylle F, Valensi P, Hall M. Horm Metab Res. 2008;  40 511-514

Correspondence

Dr. P. E. H. Schwarz

Division of Prevention of Diabetes

Department of Medicine III

Medical Faculty Carl-Gustav-Carus

Technical University Dresden

01307 Dresden

Germany

Phone: +49/351/458 27 15

Fax: +49/351/458 73 19

Email: [email protected]