Summary
Obesity is associated with increased morbidity and mortality. The condition, and central
obesity in particular, is linked to a number of disorders including glucose intolerance,
insulin resistance, hyperinsulinaemia, hypertension, dyslipidae-mia, impaired fibrinolysis,
atherosclerosis, gall bladder disease, some cancers and osteoarthritis. Weight loss
therefore benefits the individual by reducing health risks and improving the quality
of life. A body mass index (BMI) of around 22 kg/m2 is related to a minimal risk of mortality compared with higher BMI values. An extensive
review of clinical studies has shown the clear benefits of moderate weight loss (5-10%
of baseline body weight). Thus in obese individuals for whom a substantial weight
loss is not feasible, moderate weight loss should be encouraged.
Key words
Obesity - weight loss - benefits - cardiovascular risk - diabetes - hyperinsulinaemia
