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Nickel-Catalyzed Hydroalkynylation of Methylenecyclopropanes
M. Shirakura, M. Suginome*
Kyoto University, Japan
25 May 2009 (online)
Substituted cyclopropanes are important building blocks in organic synthesis. The authors report a highly regio- and stereoselective hydroalkynylation of methylene cyclopropenes providing substituted cyclopropanes. This report represents a rare example of the addition of a simple terminal alkyne to cyclopropene. The regioselectivity of the hydronickelation is also noteworthy.