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Synfacts 2009(7): 0775-0775  
DOI: 10.1055/s-0029-1217267
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Indium(III)-Catalyzed Alkynylation of Nitrones

Contributor(s): Paul Knochel, Tobias Thaler
D.-M. Ji, M.-H. Xu*
Shanghai Institute of Materia Medica, P. R. of China
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Publication History

Publication Date:
22 June 2009 (online)

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Significance

A general protocol for the alkynyl­ation of nitrones is reported. Both aliphatic and ­aromatic nitrones were efficiently reacted using InBr3 as catalyst. By applying this method to chiral nitrones good diastereoselectivities were obtained.