Synfacts 2009(12): 1354-1354  
DOI: 10.1055/s-0029-1218315
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of Planar Chiral Ru Complexes through Asymmetric Hydrogenolysis

Contributor(s): Hisashi Yamamoto, Cheol Hong Cheon
A. Mercier, W. C. Yeo, J. Chou, P. D. Chaudhuri, G. Bernardinelli, E. P. Kündig*
University of Geneva, Switzerland
Further Information

Publication History

Publication Date:
20 November 2009 (online)


The authors have developed the first catalytic desymmetrization of ruthenium complexes via palladium-catalyzed asymmetric hydrogenolysis. The desired planar chiral planar ruthenium complexes were obtained in good yields and excellent enantioselectivities. Furthermore, the ­authors have established a convenient microwave-assisted synthesis of [RuCp(MeCN)3][PF6] from readily available starting ruthenocene.