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Synthesis 2010(6): 914-916
DOI: 10.1055/s-0029-1218637
DOI: 10.1055/s-0029-1218637
SHORTPAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
A Facile Synthesis of 3-[(N-Alkylanilino)(aryl)methyl]indoles Using TCT [¹]
Further Information
Received
17 November 2009
Publication Date:
08 January 2010 (online)
Publication History
Publication Date:
08 January 2010 (online)
Abstract
Three component reaction of indoles, benzaldehydes, and N-alkylanilines in the presence of 2,4,6-trichloro-1,3,5-triazine (TCT) afforded the corresponding 3-[(N-alkylanilino)(aryl)methyl]indoles at room temperature in high yields (87-95%) within 1 to 2.5 hours.
Key words
3-[(N-alkylanilino)(aryl)methyl]indoles - benzaldehyde - N-alkylanilines - TCT
Part 196 in the series Studies on Novel Synthetic Methodologies.
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Part 196 in the series Studies on Novel Synthetic Methodologies.