Dtsch Med Wochenschr 2009; 134(34/35): 1692-1696
DOI: 10.1055/s-0029-1234004
Übersicht | Review article
Nephrologie, Immunologie
© Georg Thieme Verlag KG Stuttgart · New York

Bedeutung der Immungenetik in der Nierentransplantation: HLA-Matches und -Mismatches

The role of immunogenetics in renal transplantation: HLA-matches and mismatchesC. A. Müller1 , G. A. Müller2
  • 1Sektion Transplantationsimmunologie und Immunhämatologie, Innere Medizin, Abteilung II, Medizinische Universitätsklinik und Zentrum für Medizinische Forschung, Tübingen
  • 2Abteilung für Nephrologie und Rheumatologie, Zentrum für Innere Medizin, Georg-August-Universität Göttingen
Further Information

Publication History

eingereicht: 29.5.2009

akzeptiert: 31.7.2009

Publication Date:
25 August 2009 (online)

Literatur

  • 1 Claas F HJ, Doxiadis I IN. Human leucocyte antigen antibody detection and kidney allocation within Eurotransplant.  Hum Immunol. 2009, Apr 16 [Epub ahead of print]; 
  • 2 Claas F H. HLA antibody testing: a tool to facilitate not to prevent organ transplantation.  Int J Immunogenetics. 2008;  35 275-277
  • 3 Duquesnoy R J, Askar M. HLAMatchmaker: A molecularly based algorithm for histocompatibility determination. V. Eplet matching for HLA-DR, HLA-DQ, and HLA-DP.  Hum Immunol. 2007;  68 12-25
  • 4 Duquesnoy R J, Marrari M. HLAMatchmaker-based definition of structural human leucocyte antigen epitopes detected by alloantibodies.  Curr Opin Organ Transplant. 2009;  14 403-409
  • 5 Duquesnoy R J, Marrari M. Correlations between Terasaki’s HLA class I epitopes and HLAMatchmaker-defined eplets on HLA-A, -B, -C antigens.  Tissue Antigens. 2009;  74 117-133
  • 6 Doxiadis I IN, Claas F HJ. Transplantation of highly sensitized patients via the acceptable mismatch program or desensitization? We need both.  Curr Opin Organ Transplant. 2009;  14 410-413
  • 7 El-Awar N, Lee J, Terasaki P I. HLA antibody identification with single antigen beads compared to conventional methods.  Hum Immunol. 2005;  66 989-997
  • 8 Fleischhauer K, Avila D, Vilbois F, Traversari C, Bordignon C, Wallny H J. Characterisation of natural peptide ligands for HLA-B*4402 and B*4403: implications for peptide involvement in allorecognition of a single amino acid change in the HLA-B44 heavy chain.  Tissue Antigens. 1994;  44 311-317
  • 9 Haller H, Richter N, Bröcker V, Gwinner W, Gueller F, Schwarz A. Aktuelle Probleme der Nierentransplantation.  Internist. 2009;  50 523-535
  • 10 Kamoun M, Holmes J H, Israni A K, Kearns J D, Teal V, Yang W P, Rosas S E, Joffe M M, Li H, Feldman H I. HLA-A amino acid polymorphism and delayed kidney allograft function.  Proc Nat Acad Sci. 2008;  105 18883-18888
  • 11 Leffell M S, Zachary A A. The role of the histocompatibility laboratory in desensitization.  Curr Opin Organ Transpl. 2009, 14, epub ahead of print; 
  • 12 Miles C D, Schaubel D E, Liu D, Port F K, Rao P S. The role of donor-reciepient relationship in long-term outcomes of living donor renal transplantation.  Transplantation. 2008;  85 1483-1488
  • 13 Nickel P, Bestard O, Volk H D, Reinke P. Diagnostic value of T-cell monitoring assays in kidney transplantation.  Curr Opin Organ Transplant. 2009, 14, epub ahead of print; 
  • 14 Opelz G, Döhler B. Influence of time of rejection on long-term graft survival in renal transplantation.  Transplantation. 2008;  85 661-666
  • 15 Opelz G. for the Collaborative Transplant Study . Correlation of HLA matching with kidney graft survival in patients with or without cyclosporine treatment.  Transplantation. 1985;  40 240
  • 16 Opelz G, Döhler B. Effect of human leucocyte antigen compatibility on kidney graft survival: Comparative analysis of two decades.  Transplantation. 2007;  84 137-143
  • 17 Terasaki P I, Ozawa M, Castro R. Four-year follow-up of a prospective trial of HLA and MICA antibodies on kidney graft survival.  Am J Transpl. 2007;  7 408-415

Prof. Dr. Claudia A. Müller

Sektion Transplantationsimmunologie und Immunhämatologie, Zentrum für Medizinische Forschung

Waldhörnle Str. 22

72072 Tübingen

Phone: 07071/2983682

Fax: 07071/295755

Email: claudia.mueller@uni-tuebingen.de

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