ABSTRACT
There is a strong interaction between sleep and headache. Sleep and headache disorders
overlap epidemiologically, and share elements of anatomy and physiology. Perhaps as
a result, their treatment is often mutually interdependent. Despite this, headache
and sleep disorders tend to be treated separately, by different subspecialties of
neurology. The headache disorders and their relationship to sleep, the commonalities
of headache and sleep pathophysiology, and headache disorders that are particularly
susceptible to sleep modulation (and vice versa) are reviewed. Practical management
advice for sleep-modulated headaches is provided.
KEYWORDS
Headache - sleep - migraine - arousal
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K.C. BrennanM.D.
Headache Research and Treatment Program, Department of Neurology, David Geffen School
of Medicine at UCLA
635 Charles E. Young Drive South, Neuroscience Research Building, Room 555a, Los Angeles,
CA 90095
Email: kbrennan@mednet.ucla.edu