Facial plast Surg 2009; 25(4): 270-276
DOI: 10.1055/s-0029-1242033
© Thieme Medical Publishers

Applications of Platelet-Rich Fibrin Matrix in Facial Plastic Surgery

Anthony P. Sclafani1
  • 1Director of Facial Plastic Surgery, The New York Eye and Ear Infirmary, New York, New York; and Professor of Otolaryngology, New York Medical College, Valhalla, New York
Further Information

Publication History

Publication Date:
18 November 2009 (online)


Platelet concentrates enjoyed some clinical popularity in facial plastic surgery several years ago. However, interest waned due to expense, amount of blood required, equipment, space, and staff needed, and lack of clinically significant benefit. A novel, simple method of preparing an autologous platelet derivative (Selphyl; Aesthetic Factors, Princeton, NJ) allows rapid and inexpensive generation of a platelet-rich fibrin matrix (PRFM) that can be used to enhance healing after facial procedures as well as to rejuvenate the face without tissue manipulation. PRFM provides autologous, natural, but concentrated platelet growth factor release and stimulation of surrounding tissue. This article describes its use for cosmetic facial applications.