Surgical Management of Colorectal Liver Metastases

Waleed M Mohammad; Fady K Balaa

doi:10.1055/s-0029-1242462

Clinics in Colon and Rectal Surgery, Table of Contents

Clin Colon Rectal Surg 2009; 22(4): 225-232
DOI: 10.1055/s-0029-1242462

Surgical Management of Colorectal Liver Metastases

Waleed M. Mohammad¹ , Fady K. Balaa¹

¹Liver and Pancreas Unit, The Ottawa Hospital, University of Ottawa, Ottawa, Ontario, Canada

Abstract

ABSTRACT

Colorectal cancer is the third most commonly diagnosed cancer with approximately half of the patients developing liver metastases during the course of their disease. Modern multimodal therapies have improved the overall survival. Liver resection remains the most important modality in the treatment of colorectal liver metastases. The evolution of the criteria for resectability has resulted in more patients being offered a hepatectomy. This is further augmented with the utilization of adjuncts to liver resection, including portal vein embolization and local ablative techniques. Two-stage hepatectomy is also being used to increase resectability. Overall survival is improved by the deployment of new chemotherapeutic agents and the use of combination chemotherapy. Neoadjuvant chemotherapy is a promising development in the treatment of colorectal liver metastases. Patients with colorectal liver metastases can achieve long-term survival. A multidisciplinary approach is essential in the management of these patients.

KEYWORDS

Liver - colorectal liver metastases - hepatectomy - chemotherapy

Full Text

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Fady K BalaaM.D.

Liver and Pancreas Unit, The Ottawa Hospital, University of Ottawa

737 Parkdale Ave., Ste. 305, Ottawa, Ontario, Canada K1Y 1J8

Email: fbalaa@toh.on.ca