ABSTRACT
The social impact of bone and cartilage pathologies entails high costs in terms of
therapeutic treatments and loss of income. As a result, the current research trend
includes preventive interventions and therapeutic solutions that can lead to an enhancement
of tissue regeneration and the reduction of degenerative mechanisms.
Many options have been made available to address problems regarding cartilage damage,
each with its own advantages and disadvantages. Several studies are currently in progress
to clarify some of the questions that remain unanswered about the long-term durability
of these procedures and the possible modifications that can be made to achieve better
results.
Biotechnology is progressing at a rapid pace that allows the introductions of several
products for clinical application; however, randomized, prospective studies for these
innovations should be conducted to validate the safety and efficacy of cartilage regeneration.