ABSTRACT
Transient tachypnea of the newborn (TTN) is a common respiratory problem in newborns.
This study aims to determine if cesarean delivery (CD) is a risk factor for TTN, and
if labor prior to CD decreases this risk. A linked data set consisting of Arizona
birth certificates (1994 to 1998) and infants enrolled in a high-risk perinatal program
provided 800 TTN cases and 800 controls, stratified by year. The relationships of
CD and labor to TTN were examined using logistic regression. CD was associated with
an increased risk of TTN, whether it was accompanied by labor (odds ratio [OR] 2.68;
95% confidence interval [CI] 1.62 to 4.45) or not accompanied by labor (OR 2.88; 95%
CI 2.01 to 4.13), even after adjusting for confounding variables. Labor did not affect
the development of TTN, nor did it modify the association of CD with increased risk
for TTN. CD is a risk factor for TTN. Labor prior to CD is not protective for TTN.
KEYWORDS
Transient tachypnea of the newborn - cesarean delivery - labor
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Dean V CoonrodM.D. M.P.H.
Associate Professor of Clinical Obstetrics and Gynecology, University of Arizona College
of Medicine
2601 E. Roosevelt, Phoenix, AZ 85008
eMail: dean_coonrod@dmgaz.org
