© Georg Thieme Verlag KG Stuttgart · New York
Sedation and preparation
13 January 2011 (online)
Although many editorials for sedation in gastrointestinal endoscopy have been published over recent years, sedation and surveillance seems to be a topic for a never-ending story. Many recently published data have shown that sedation with short-acting propofol seems to be the ideal drug for endoscopic procedures, whether for diagnostic        or therapeutic  purposes, even in elderly high-risk patients , and is therefore recommended as the first choice in the currently published international guidelines   . Newer indications for the use of propofol have been investigated. In a recently published randomized controlled trial (RCT) the use of propofol was compared with midazolam for sedation for upper gastrointestinal endoscopy in patients with liver cirrhosis. Results showed that the advantage of propofol lies in the avoidance of acute deterioration of minimal encephalopathy in these patients .