Synfacts 2010(8): 0963-0963  
DOI: 10.1055/s-0030-1257787
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Ligand-Free Ullmann Arylation of Indole Using PEG3400-Cu2O-Cs2CO3

Contributor(s): Yasuhiro Uozumi, Toshimasa Suzuka
E. Colacino, L. Villebrun, J. Martinez, F. Lamaty*
Université de Montpellier II, France
Further Information

Publication History

Publication Date:
22 July 2010 (online)

Significance

The ligand-free Ullmann arylation of indole with aryl halides was performed with a PEG3400-Cu2O-Cs2CO3 system. The coupling ­reaction was carried out in a high molecular weight PEG matrix as a solvent. The catalytic composite PEG3400-Cu2O-Cs2CO3 was recovered by precipitation with Et2O.