Synfacts 2010(8): 0915-0915  
DOI: 10.1055/s-0030-1257819
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Synthesis of 1,3-syn-Diol Acetals via Re-Catalyzed Allylic Alcohol Transposition

Contributor(s): Hisashi Yamamoto, Zhi Li
A. T. Herrmann, T. Saito, C. E. Stivala, J. Tom, A. Zakarian*
University of California, Santa Barbara, USA
Further Information

Publication History

Publication Date:
22 July 2010 (online)

Significance

The synthesis of 1,3-syn-diol moieties has been extensively studied in organic ­synthesis, because they frequently appear in ­natural molecules. This work featured a very unique rhenium-catalyzed synthesis of 1,3-syn-diol acetals in high diastereoselectivities.