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Synfacts 2010(9): 1077-1077  
DOI: 10.1055/s-0030-1257987
Polymer-Supported Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Immobilization of Organic Functional Groups onto Silica

Contributor(s): Yasuhiro Uozumi, Yoichi M. A. Yamada, Toshihiro Watanabe
J.-W. Park, C.-H. Jun*
Yonsei University, Seoul, South Korea
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Publication History

Publication Date:
23 August 2010 (online)

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Significance

Functionalized vinylsilanes 3 were prepared by hydroacylation of dimethyldivinylsilane (2) with various aldehydes 1 in the presence of (Ph3P)3RhCl, 2-amino-3-picoline, and 4-(trifluoromethyl)benzoic acid (63-92% yield, 11 examples). Immobilization of 3 onto silica by using [IrCl(coe)2]2 and DMA˙HCl gave the corresponding functionalized silica compounds 4 with 0.58-1.04 mmol/g of loading (11 examples).