Synfacts 2011(8): 0897-0897  
DOI: 10.1055/s-0030-1260716
Metal-Mediated Synthesis
© Georg Thieme Verlag Stuttgart ˙ New York

Ni-Catalyzed Cross-Couplings of Tertiary Alkyl Grignards and Aryl Bromides

Contributor(s): Paul Knochel, Andreas K. Steib
A. Joshi-Pangu, C.-Y. Wang, M. R. Biscoe*
The City College of New York, USA
Further Information

Publication History

Publication Date:
20 July 2011 (online)

Significance

A new Ni-catalyzed Kumada cross-coupling reaction of tertiary alkylmagnesium ­halides and aryl bromides has been developed. NiCl2 in combination with a commercially available N-heterocyclic carbene ligand is used as catalytic system.