Synfacts 2011(9): 0970-0970  
DOI: 10.1055/s-0030-1260905
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart ˙ New York

Copper(I)-Catalyzed Asymmetric Conjugate Addition-Protonation of Nitroalkenes

Contributor(s): Hisashi Yamamoto, Patrick Brady
T. Arai*, A. Awata, M. Wasai, N. Yokoyama, H. Masu
Chiba University, Japan
Further Information

Publication History

Publication Date:
19 August 2011 (online)


An asymmetric conjugate addition-protonation sequence of indoles and pyrrole to trisubstituted nitroalkenes is described. The process is catalyzed by a copper(I)/imidazole-amino­phenol complex.