Skull Base 2011; 21(2): 093-098
DOI: 10.1055/s-0030-1266763
ORIGINAL ARTICLE

© Thieme Medical Publishers

Nasoseptal Flap Closure of Traumatic Cerebrospinal Fluid Leaks

Stephan A. Wheless1 , Kibwei A. McKinney1 , Ricardo L. Carrau3 , Carl H. Snyderman4 , Amin B. Kassam3 , Anand V. Germanwala2 , Adam M. Zanation1
  • 1Department of Otolaryngology–Head and Neck Surgery, Chapel Hill, North Carolina
  • 2Division of Neurosurgery at the University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
  • 3Brain Tumor Center and Neuroscience Institute, John Wayne Cancer Institute at Saint John's Health Center, Santa Monica, California
  • 4Department of Otolaryngology, University of Pittsburgh Medical Center, Eye and Ear Institute, Pittsburgh, Pennsylvania
Further Information

Publication History

Publication Date:
16 September 2010 (online)

ABSTRACT

The vascularized nasoseptal flap has become a principal reconstructive technique for the closure of endonasal skull base surgery defects. Despite its potential utility, there has been no report describing the use of the modern nasoseptal flap to repair traumatic cerebrospinal fluid (CSF) leaks and documenting the outcomes of this application. Specific concerns in skull base trauma include septal trauma with disruption of the flap pedicle, multiple leak sites, and issues surrounding persistent leaks after traumatic craniotomy. We performed a retrospective case series review of 14 patients who underwent nasoseptal flap closure of traumatic CSF leaks in a tertiary academic hospital. Main outcome measures include analysis of clinical outcome data. Defect etiology was motor vehicle collision in eight patients (57%), prior sinus surgery in four (29%), and assault in two (14%). At the time of nasoseptal flap repair, four patients had failed prior avascular grafts and two had previously undergone craniotomies for repair. Follow-up data were available for all patients (mean, 10 months). The overall success rate was 100% (no leaks), with 100% defect coverage. The nasoseptal flap is a versatile and reliable local reconstructive technique for ventral base traumatic defects, with a 100% CSF leak repair rate in this series.

REFERENCES

  • 1 Costa H, Cerejo A, Baptista A et al.. The galea frontalis myofascial flap in anterior fossa CSF leaks.  Br J Plast Surg. 1993;  46 503-507
  • 2 Platt M P, Parnes S M. Management of unexpected cerebrospinal fluid leak during endoscopic sinus surgery.  Curr Opin Otolaryngol Head Neck Surg. 2009;  17 28-32
  • 3 Moyer J S, Chepeha D B, Teknos T N. Contemporary skull base reconstruction.  Curr Opin Otolaryngol Head Neck Surg. 2004;  12 294-299
  • 4 Hadad G, Bassagasteguy L, Carrau R L et al.. A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap.  Laryngoscope. 2006;  116 1882-1886
  • 5 Zanation A M, Carrau R L, Snyderman C H et al.. Nasoseptal flap reconstruction of high flow intraoperative cerebral spinal fluid leaks during endoscopic skull base surgery.  Am J Rhinol Allergy. 2009;  23 518-521
  • 6 Hirsch O. Successful closure of cerebrospinal fluid rhinorrhea by endonasal surgery.  AMA Arch Otolaryngol. 1952;  56 1-12
  • 7 Vrabec D P, Hallberg O E. Cerebrospinal fluid rhinorrhea. Intranasal approach, review of the literature, and report of a case.  Arch Otolaryngol. 1964;  80 218-229
  • 8 Montgomery W W. Cerebrospinal fluid rhinorrhea.  Otolaryngol Clin North Am. 1973;  6 757-771
  • 9 McCabe B F. The osteo-mucoperiosteal flap in repair of cerebrospinal fluid rhinorrhea.  Laryngoscope. 1976;  86 537-539
  • 10 Yessenow R S, McCabe B F. The osteo-mucoperiosteal flap in repair of cerebrospinal fluid rhinorrhea: a 20-year experience.  Otolaryngol Head Neck Surg. 1989;  101 555-558
  • 11 Snyderman C H, Carrau R L, Kassam A B et al.. Endoscopic skull base surgery: principles of endonasal oncological surgery.  J Surg Oncol. 2008;  97 658-664
  • 12 Snyderman C H, Kassam A B, Carrau R, Mintz A. Endoscopic reconstruction of cranial base defects following endonasal skull base surgery.  Skull Base. 2007;  17 73-78
  • 13 Hegazy H M, Carrau R L, Snyderman C H, Kassam A, Zweig J. Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea: a meta-analysis.  Laryngoscope. 2000;  110 1166-1172
  • 14 Senior B A, Jafri K, Benninger M. Safety and efficacy of endoscopic repair of CSF leaks and encephaloceles: a survey of the members of the American Rhinologic Society.  Am J Rhinol. 2001;  15 21-25
  • 15 Sherman J H, Pouratian N, Okonkwo D O, Jane Jr J A, Laws E R. Reconstruction of the sellar dura in transsphenoidal surgery using an expanded polytetrafluoroethylene dural substitute.  Surg Neurol. 2008;  69 73-76 discussion 76
  • 16 Germani R M, Vivero R, Herzallah I R, Casiano R R. Endoscopic reconstruction of large anterior skull base defects using acellular dermal allograft.  Am J Rhinol. 2007;  21 615-618
  • 17 Shah A R, Pearlman A N, O'Grady K M, Bhattacharyya T K, Toriumi D M. Combined use of fibrin tissue adhesive and acellular dermis in dural repair.  Am J Rhinol. 2007;  21 619-621
  • 18 Zweig J L, Carrau R L, Celin S E et al.. Endoscopic repair of cerebrospinal fluid leaks to the sinonasal tract: predictors of success.  Otolaryngol Head Neck Surg. 2000;  123 195-201
  • 19 Kassam A B, Thomas A, Carrau R L et al.. Endoscopic reconstruction of the cranial base using a pedicled nasoseptal flap.  Neurosurgery. 2008;  (1 Suppl 1) ONS44-ONS52 discussion ONS52-ONS43
  • 20 Fortes F S, Carrau R L, Snyderman C H et al.. The posterior pedicle inferior turbinate flap: a new vascularized flap for skull base reconstruction.  Laryngoscope. 2007;  117 1329-1332
  • 21 Shah R N, Surowitz J B, Patel M R et al.. Endoscopic pedicled nasoseptal flap reconstruction for pediatric skull base defects.  Laryngoscope. 2009;  119 1067-1075
  • 22 Kang M D, Escott E, Thomas A J et al.. The MR imaging appearance of the vascular pedicle nasoseptal flap.  AJNR Am J Neuroradiol. 2009;  30 781-786
  • 23 Harvey R J, Smith J E, Wise S K, Patel S J, Frankel B M, Schlosser R J. Intracranial complications before and after endoscopic skull base reconstruction.  Am J Rhinol. 2008;  22 516-521

Adam M ZanationM.D. 

Assistant Professor, Department of Otolaryngology–Head and Neck Surgery, University of North Carolina at Chapel Hill

G190 Physicians Office Building, Chapel Hill, NC 27599-7070

Email: azanatio@med.unc.edu

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