Triterpenes and Triterpenoid Saponins from the Leaves of Ilex kudincha

Abstract

One new triterpene, kudinchalactone A (1), and four new triterpenoid saponins, ilekudinchosides A−D (2–5), were isolated from the leaves of Ilex kudincha C. J. Tseng along with eight known triterpenoids. These new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectra. Compounds 2, 3, 12, and 13 showed antibacterial activities against Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA).

Key words

Ilex kudincha - Aquifoliaceae - triterpenoids - kudinchalactone A - ilekudinchosides A−D - antibacterial activity

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