ABSTRACT
There is a surge in fungal infections of the central nervous system due to an increase
in the incidence of immunocompromised state and widespread use of antimicrobials.
Despite myriad clinical presentations and skull base syndromes associated with Aspergillus
infections, aspergilloma in the sella is relatively rare. We report a rare case of
aspergilloma of the sella and parasellar region in a patient operated for acromegaly.
A 30-year-old diabetic patient underwent two surgeries for a growth hormone-secreting
pituitary adenoma, which included a transsphenoidal approach. During his last admission,
magnetic resonance imaging revealed a heterogeneous mass in the sella, suprasellar
region, sphenoid sinus, and cavernous sinus with multiple areas of necrosis. His presentation,
surgical treatment, and response to antifungal therapy are discussed. The role of
prior surgery and related comorbidities in developing the invasive granuloma are highlighted.
KEYWORDS
Acromegaly - amphotericin - Aspergillus - cavernous sinus - fungal infections - sella
- surgery
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Sunil V FurtadoM.S. M.Ch. D.N.B.
Department of Neurosurgery, SSSIHMS, EPIP Area, Whitefield
Bangalore-560066, India
Email: sunilvf@gmail.com