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Skull Base Rep 2011; 1(1): 059-064
DOI: 10.1055/s-0031-1275637
© Thieme Medical Publishers

Subfrontal Schwannoma Mimicking Neuroblastoma: Case Report

Hitoshi Yamahata1 , Kazuho Hirahara1 , Tetsuzou Tomosugi1 , Masahiko Yamada1 , Takeshi Ishii1 , Takashi Ishigami1 , Koichi Uetsuhara1 , Kazunobu Sueyoshi2 , Sumika Matsukida2 , Kazutaka Yatsushiro3 , Kazunori Arita3
  • 1Department of Neurosurgery, Kagoshima City Hospital, Kagoshima, Japan
  • 2Department of Clinical Pathology, Kagoshima City Hospital, Kagoshima, Japan
  • 3Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan
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Publication History

Publication Date:
25 March 2011 (online)

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ABSTRACT

Computed tomography (CT), performed in a healthy 28-year-old man after minor head injury, detected a frontal base tumor. Neurological examination revealed left hyposmia. On magnetic resonance imaging scans, there was a heterogeneously enhanced tumor located in the left paramedian frontal base with extension into the left ethmoid sinus. Angiography showed a hypervascular mass in the left anterior cranial fossa; it was mainly fed by the left ethmoidal artery. Positron emission tomography scanning showed moderate accumulation of 11-methylmethionine and low accumulation of 18-fluorodeoxyglucose (FDG) at the tumor site. Bone image CT disclosed compressive, nondestructive deformation of the left frontal base. The preoperative diagnosis was olfactory neuroblastoma or meningioma. The tumor was totally resected via bifrontal craniotomy. The tumor was histologically diagnosed as typical schwannoma; it was positive for S-100 protein. We report a rare subfrontal schwannoma with extension into the nasal cavity that mimicked neuroblastoma. Low FDG accumulation and compressive deformation of the anterior skull base may help in the differential diagnosis of these tumors.

KEYWORDS

Subfrontal schwannoma - olfactory nerve - neuroblastoma - skull base

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Hitoshi YamahataM.D. 

Department of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University

8-35-1 Sakuragaoka, Kagoshim-shi, Kagoshima 890-8520, Japan

Email: yamahata-nsu@umin.net

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