Biphenyl and Biphenyl Ether Quinolizidine N-oxide Alkaloids from Lagerstroemia indica L.

Abstract

Four new biphenyl and biphenyl ether quinolizidine N-oxide alkaloids, 5-epi-dihydrolyfoline N-oxide (1), decamine N-oxide (2), lagerstroemine N-oxide (3), and lagerine N-oxide (4), were isolated from the aerial parts of Lagerstroemia indica, and their structures were established by extensive spectroscopic studies. In addition, the inhibitory effects of isolated compounds on rat lens aldose reductase (RLAR) were examined.

Lagerstroemia indica - Lythraceae - quinolizidine alkaloid - molecular modeling - aldose reductase

References

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