Zusammenfassung
Über kortiko-subkortiko-kortikale Schleifensysteme beeinflusst die dopaminerge Modulation
auf der Ebene des Striatums nicht nur motorische Funktionen, sondern auch andere kortikale
Efferenzen. Es wird eine Übersicht über neuropsychologische Befunde bei Morbus Parkinson
gegeben und versucht, diese systemphysiologisch zu interpretieren. Die Theorie des
„supervisory attentional system“ von Norman und Shallice (1986) erscheint geeignet,
die Rolle von frontalem Kortex und Basalganglien in der Handlungssteuerung zu erklären.
Abstract
Through cortico-subcortico-cortical loop systems, the dopaminergic modulation influences
not only motor, but also other executive functions. Neurospychological findings in
Parkinson’s disease are reviewed and physiologically interpreted. The theory of a
'supervisory attentional system” according to Norman and Shallice (1986) seems to
be an adequate model of the interaction of cortex and basal ganglia in executive function
and control.
Schlüsselwörter
Morbus Parkinson - Neuropsychologie - Systemphysiologie
Keywords
Parkinson’s disease - neuropsychology - system physiology
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Prof. Dr. Claus W Wallesch
BDH-Klinik
Am Tannwald 1
79215 Elzach
eMail: cwallesch@neuroklinik-elzach.de
