Detraining Decreases Hbmass of Triathletes

A. Eastwood; P. C. Bourdon; K. R. Snowden; C. J. Gore

doi:10.1055/s-0031-1291184

International Journal of Sports Medicine, Table of Contents

Int J Sports Med 2012; 33(04): 253-257
DOI: 10.1055/s-0031-1291184

Physiology & Biochemistry

Detraining Decreases Hb_mass of Triathletes

Authors

A. Eastwood

¹South Australian Sports Institute, Sport Science, Adelaide, Australia
P. C. Bourdon

¹South Australian Sports Institute, Sport Science, Adelaide, Australia
K. R. Snowden

¹South Australian Sports Institute, Sport Science, Adelaide, Australia
C. J. Gore

²Australian Institute of Sport, Physiology, Canberra, Australia

Abstract

Haemoglobin mass (Hb_mass) determination using CO rebreathing may assist to detect illegal blood doping practices, however variations in Hb_mass with periods of intensive training and detraining must be quantified. This study aimed to determine the effect of a 30-day period of detraining on Hb_mass in ultra-endurance triathletes. 9 male recreational triathletes (29–44 years) participated in the study. Hb_mass was assessed using CO rebreathing 30 days and 10 days before an ultra-endurance triathlon and after ~10, 20 and 30 days of detraining following the race. V˙O_2max was assessed 10 days before the race and also after the 30-day detraining period, which consisted of an 87% reduction in training hours. After 30-days of detraining there was a 3.1% decrease in mean Hb_mass from 868±99 to 840±94 g, (p=0.03), and a 4.7% decrease in mean V˙O_2max from 4.83±0.29 to 4.61±0.41 L/min as well as a 2.8% increase of body mass from 75.1±6.4 to 77.1±6.1 kg and a 28% increase in skinfold total from 43.9±14.2 to 55.1±14.0 mm. Individual decreases in Hb_mass following detraining would need to be considered if using Hb_mass for anti-doping purposes.

Key words

erythropoesis - training - anti doping

Full Text

References

References
1 Alfrey CP, Rice L, Udden MM, Driscoll TB. Neocytolysis: physiological down-regulator of red-cell mass. Lancet 1997; 349: 1389-1390
2 Clark SA, Bourdon PC, Schmidt W, Singh B, Cable G, Onus KJ, Woolford SM, Stanef T, Gore CJ, Aughey RJ. The effect of acute simulated moderate altitude on power, performance and pacing strategies in well-trained cyclists. Eur J Appl Physiol 2007; 102: 45-55
3 Cohen J. Statistical Power Analysis for the Behavioural Sciences. Hillsdale, New Jersey: Lawrence Erlbaum Associates; 1988: 25
4 Coyle EF, Hemmert MK, Coggan AR. Effects of detraining on cardiovascular responses to exercise: role of blood volume. J Appl Physiol 1986; 60: 95-99
5 Eastwood A, Bourdon PC, Withers RT, Gore CJ. Longitudinal changes in haemoglobin mass and V˙O_2max in adolescents. Eur J Appl Physiol 2009; 105: 715-721
6 Eastwood A, Hopkins WG, Bourdon PC, Withers RT, Gore CJ. Stability of haemoglobin mass over 100 days in active men. J Appl Physiol 2008; 104: 982-985
7 Garvican LA, Martin DT, McDonald W, Gore CJ. Seasonal variation of haemoglobin mass in internationally competitive female road cyclists. Eur J Appl Physiol 2010; 109: 221-231
8 Gore CJ, Hahn AG, Burge CM, Telford RD. V˙O_2max and haemoglobin mass of trained athletes during high intensity training. Int J Sports Med 1997; 18: 477-482
9 Gore CJ, Hopkins WG, Burge CM. Errors of measurement for blood volume parameters: a meta-analysis. J Appl Physiol 2005; 99: 1745-1758
10 Harriss DJ, Atkinson G. Update – Ethical Standards in Sport and Exercise Science Research. Int J Sports Med 2011; 32: 819-821
11 Hopkins WG. Measures of reliability in sports medicine and science. Sports Med 2000; 30: 1-15
12 Hopkins WG. A spreadsheet for analysis of straightforward controlled trials 2003; 7 www.sportsci.org/jour/03/wghtrials.htm
13 Hopkins WG, Marshall SW, Batterham AM. Progressive statistics for studies in sports medicine and exercise science. Med Sci Sports Exerc 2009; 41: 3-12
14 Jones AM, Carter H. The effect of endurance training on parameters of aerobic fitness. Sports Med 2000; 29: 373-386
15 Mujika I, Padilla S. Cardiorespiratory and metabolic characteristics of detraining in humans. Med Sci Sports Exerc 2001; 33: 413-421
16 Pottgiesser T, Umhau M, Ahlgrim C, Ruthardt S, Roecker K, Schumacher YO. Hb mass measurement suitable to screen for illicit autologous blood transfusions. Med Sci Sports Exerc 2007; 39: 1748-1756
17 Prommer N, Sottas PE, Schoch C, Schumacher YO, Schmidt W. Total haemoglobin mass – a new parameter to detect blood doping?. Med Sci Sports Exerc 2008; 40: 2112-2118
18 Saltin B, Calbet JA. Point: in health and in a normoxic environment, V˙O_2max is limited primarily by cardiac output and locomotor muscle blood flow. J Appl Physiol 2006; 100: 744-745
19 Sawka MN, Convertino VA, Eichner ER, Schnieder SM, Young AJ. Blood volume: importance and adaptations to exercise training, environmental stresses, and trauma/sickness. Med Sci Sports Exerc 2000; 32: 332-348
20 Schmidt W, Prommer N. The optimised CO-rebreathing method: a new tool to determine total haemoglobin mass routinely. Eur J Appl Physiol 2005; 95: 486-495
21 Schmidt W, Prommer N. Effects of various training modalities on blood volume. Scand J Med Sci Sports 2008; 18: 57-69
22 Schmidt W, Prommer N. Impact of alterations in total haemoglobin mass on V˙O_2max . Exerc Sport Sci Rev 2010; 38: 68-75
23 Schumacher YO, Ahlgrim C, Ruthardt S, Pottgiesser T. Haemoglobin mass in an elite endurance athlete before, during, and after injury-related immobility. Clin J Sport Med 2008; 18: 172-173
24 Sharpe K, Ashenden MJ, Schumacher YO. A third generation approach to detect erythropoietin abuse in athletes. Haematologica 2006; 91: 356-363
25 Sottas PE, Robinson N, Saugy M. The Athlete’s Biological Passport and Indirect Markers of Blood Doping. In: Thieme D, Hemmersbach P. (eds.). Doping in Sports, Handbook of Experimental Pharmacology. Berlin, Heidelberg: Springer-Verlag; 2010: 305-326
26 Withers RT, Craig NP, Bourdon PC, Norton KI. Relative body fat and anthropometric prediction of body density of male athletes. Eur J Appl Physiol 1987; 56: 191-200