Endoscopy 2012; 44(03): 297-300
DOI: 10.1055/s-0031-1291482
Case report/series
© Georg Thieme Verlag KG Stuttgart · New York

Usefulness of biodegradable polydioxanone stents in the treatment of postsurgical colorectal strictures and fistulas

F. Pérez Roldán
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
P. González Carro
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
M. C. Villafáñez García
2   Department of Emergency, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
S. Aoufi Rabih
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
M. L. Legaz Huidobro
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
N. Sánchez-Manjavacas Múñoz
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
O. Roncero García-Escribano
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
M. Ynfante Ferrús
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
E. Bernardos Martín
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
,
F. Ruiz Carrillo
1   Department of Gastroenterology, Hospital General La Mancha-Centro, Alcázar de San Juan, Spain
› Author Affiliations
Further Information

Publication History

submitted 04 July 2011

accepted after revision 28 September 2011

Publication Date:
19 January 2012 (online)

Benign colonic strictures and fistulas are a growing problem presenting most commonly after bowel resection. Standard treatment is with endoscopic bougies or, more usually, balloon dilation. When these approaches are not successful, other solutions are available and different endoscopic and surgical approaches have been used to treat fistulas. We present an additional option – biodegradable stents – for the treatment of colonic strictures and fistulas that have proven refractory to other endoscopic interventions. We analyzed the results from 10 patients with either a postsurgical colorectal stricture (n = 7) or rectocutaneous fistula (n = 3) treated with the biodegradable SX-ELLA esophageal stent (covered or uncovered). Stents were successfully placed in nine patients, although early migration subsequently occurred in one. Placement was impossible in one patient due to deformity of the area and the fact that the stricture was approximately 30 cm from the anus. The fistulas were successfully closed in all patients, although symptoms reappeared in one patient. In the six patients who received stents for strictures, symptoms resolved in five; in the remaining patient, the stent migrated shortly after the endoscopy. Treatment of colonic strictures and rectocutaneous fistulas with biodegradable stents is an effective alternative in the short-to-medium term. The stent does not have to be removed and is subject to very few complications. The drawbacks of this approach are the need to repeat the procedure in some patients and the lack of published series on efficacy.

 
  • References

  • 1 Ambrosetti P, Francis K, DePeyer R, Frossard JL. Colorectal anastomotic stenosis after elective laparoscopic sigmoidectomy for diverticular disease: a prospective evaluation of 68 patients. Dis Colon Rectum 2008; 51: 1345-1349
  • 2 Delaunay-Tardy K, Barthélémy C, Dumas O et al. Endoscopic therapy of benign colonic post-operative strictures: Report on 27 cases. Gastroenterol Clin Biol 2003; 27: 610-613
  • 3 Matthiesen P, Lindgren P, Hallböök O. Rectal Cancer Trial on Defunctioning Stoma Study Group et al. Symptomatic anastomotic leakage diagnosed after hospital discharge following low anterior resection for rectal cancer. Colorectal Dis 2010; 12: e82-e87
  • 4 Köckerling F, Rose J, Schneider C. Laparoscopic Colorectal Surgery Study Group (LCSSG). et al. Laparoscopic colorectal anastomosis: risk of postoperative leakage. Results of a multicenter study. Surg Endosc 1999; 13: 639-644
  • 5 Suchan KL, Muldner A, Manegold BC. Endoscopic treatment of postoperative colorectal anastomotic strictures. Surg Endosc 2003; 17: 1110-1113
  • 6 García-Cano J. Dilation of benign strictures in the esophagus and colon with the polyflex stent: a case series study. Dig Dis Sci 2008; 53: 341-346
  • 7 Abbas MA. Endoscopic management of acute colorectal anastomotic complications with temporary stent. JSLS 2009; 13: 420-424
  • 8 Schlegel RD, Dehni N, Parc R et al. Results of reoperations in colorectal anastomotic strictures. Dis Colon Rectum 2001; 44: 1464-1468
  • 9 Rio P, Dell’Abate P, Soliani P et al. Endoscopic treatment of esophageal and colo-rectal fistulas with fibrin glue. Acta Biomed 2005; 76: 95-98
  • 10 Sabino MA, González S, Marquez L et al. Study of the hydrolytic degradation of polydioxanone PPDX. Polym Degrad Stab 2000; 69: 209-216
  • 11 Vandenplas Y, Hauser B, Devreker T et al. A degradable esophageal stent in the treatment of a corrosive esophageal stenosis in a child. Endoscopy 2009; 41: E73
  • 12 Cerná M, Martin Köcher M, Válek V et al. Covered biodegradable stent: new therapeutic option for the management of esophageal perforation or anastomotic leak. Cardiovasc Intervent Radiol 2011; DOI: DOI: 10.1007/s00270-010-0059-9.
  • 13 Pérez Roldán F, González Carro P, Villafáñez García MC et al. Imagen endoscópica de recto tras la reabsorción de una prótesis de polidioxanona. Rev ACAD 2011; 27: 29-30
  • 14 Janik V, Horák L, Hnanícek J et al. Biodegradable polydioxanone stents: a new option for therapy-resistant anastomotic strictures of the colon. Eur Radiol 2011; 21: 1956-1961
  • 15 Pérez Roldán F, González Carro P, Villafáñez García MC et al. Eficacia de las prótesis biodegradables en el tratamiento de enfermedades colorrectales. Rev Esp Enferm Dig 2011; 103: 107